研究成果

• 2018

  Tanghui Duan, Liu He, Yu Tokura, Xin Liu, Yuzhou Wu*, Zhengshuang Shi*. Construction of tunable peptide nucleic acid junctions. Chem. Commun., 2018, DOI: 10.1039/c8cc00108a.

  Yu Tokura+, Sean Harvey+, Chaojian Chen, Yuzhou Wu*, David Y. W. Ng*, Tanja Weil*. Fabrication of Defined Polydopamine Nanostructures by DNA Origami-Templated Polymerization. Angew. Chem. Int. Ed. 2018, 57, 1587 –1591.

  Yu Tokura, Yuzhou Wu, * David Y. W. Ng *,Tanja Weil *.Polymer tube nanoreactors via DNA-origami templated synthesis. Chem. Commun., 2018, DOI: 10.1039/c7cc09620h.

• 2017

  Sylvia Schmid,* Jasmina Gačanin, Yuzhou Wu, Tanja Weilbd, Peter Bäuerlea. Synthesis and bioconjugation of first alkynylated poly(dithieno[3,2-b:2′,3′-d]pyrrole)s. Polym. Chem., 2017,8, 7113-7118.

  David Y. W. Ng*, Yuzhou Wu, Ulrich Ziener*, Tanja Weil*. Directing intracellular supramolecular assembly with N-heteroaromatic quaterthiophene analogues. Nature Communications, 2017, 8: 1850.

  Jasmina Gačanin, Yuzhou Wu*, Holger Barth*, Anita Ignatius*. Spatiotemporally Controlled Release of Rho-Inhibiting C3 Toxin from a Protein–DNA Hybrid Hydrogel for Targeted Inhibition of Osteoclast Formation and Activity. Adv. Healthcar...

  Brenton A. G. Hammer, Yuzhou Wu, Stephan Fischer, Weina Liu, Tanja Weil*, Klaus Müllen*. Controlling Cellular Uptake and Toxicity of Polyphenylene Dendrimers by Chemical Functionalization. Chembiochem, 2017, 18(10), 960-964.

  Zhi Zuo, Yuzhou Wu, Volker Rasche*. The CAM cancer xenograft as a model for initial evaluation of MR labelled compounds. Scientific Reports, 2017,7:4669

  Sabyasachi Chakrabortty, Yuzhou Wu, Tanja Weil*. NIR-emitting and photo-thermal active nanogold as mitochondria-specific probes. Biomater. Sci., 2017, 5, 966-971.

  Yuzhou Wu, Tanja Weil, Nanodiamonds for Biological Applications, 2017, Chemistry of Carbon Nanostructures, Book Chapter, DOI: 10.1515/9783110284645-009.

• 2016

  S. Schmid*, E. Mena-Osteritz*, Y. Wu, P. Bäuerle* et. al. Self-assembling oligothiophene–bolaamphiphiles for loading and controlled release of doxorubicin into living cells. Chem. Commun., 2016, 52, 3235-3238.

  Christiane Seidler, David. Y. W. Ng, Yuzhou Wu and Tanja Weil*. pH responsive supramolecular core-shell protein hybrids, Supramolecular Chemistry, 2016, 28(9-10), 742-746.

  Seah Ling Kuan, Yuzhou Wu, Tanja Weil1*, A supramolecular approach toward bioinspired PAMAM-dendronized fusion toxins, Macromol. Biosci. 2016, 16, 803−810.

  ​Tao Wang§, Andreas Riegger§, Yuzhou Wu, Tanja Weil*, Water-soluble allyl sulfones for dual site-specific labelling of proteins and cyclic peptides, Chem. Sci., 2016, 7, 3234-3239.

  Felix Boldt, Weina Liu, Yuzhou Wu*, Tanja Weil*. Converting Human Proteins into Precision Polymer Therapeutics. Curr Pharm Des., 2016, 22, 2866-2872.

  David Palesch, Felix Boldt, Janis A. Müller, Klaus Eisele, Christina M. Stürzel, Yuzhou Wu*, Jan Münch*, Tanja Weil*. PEGylated cationic serum albumin to boost retroviral gene transfer. ChemBioChem, 2016, 17(16), 1504-1508.

  Yuzhou Wu*, Fedor Jelezko, Martin Plenio, Tanja Weil*, Diamond Quantum Devices in Biology, Angew. Chem. Int. Ed., 2016, 55, 6586-6598.

• 2015

  Tao Wang, Yuzhou Wu, Christopher Barner-Kowollik*, Tanja Weil*, A Disulfide Intercalator Toolbox for Site-Directed Polypeptide Modification, Chemistry – a European Journal, 2015, 21, 228-238.

  ​Tao Wang, Yuzhou Wu, MarkusLamla, David Y. W.Ng,* Sven Rau* and TanjaWeil*, Receptor Selective Ruthenium-Somatostatin Photosensitizer for Cancer Targeted Photodynamic Applications, Chem. Commun. 2015, 51, 12552-12555.

  Tao Zhang, Yuzhou Wu, Alexander Högele*, Tanja Weil* and Tim Liedl*, DNA-based self-assembly of fluorescent nanodiamonds, J. Am. Chem. Soc., 2015, 31, 9776–9779.

  Yuzhou Wu*, Fedor Jelezko*, Tanja Weil*, Programmable Biopolymers for Advancing Biomedical Applications of Fluorescent Nanodiamonds. Adv. Funct. Mater. 2015, 25, 6576–6585.

  Yuzhou Wu, David Yuen Wah Ng, Seah Ling Kuan, Tanja Weil*, “Protein-Polymer Therapeutics – A Macromolecular Perspective”, Biomaterials Science, 2015, 3, 214-230.

  René Stangenberg#, Yuzhou Wu#, Tanja Weil* and Klaus Müllen*, A Polyphenylene Dendrimer Drug Transporter with Precisely Positioned Amphiphilic Surface Patches. Adv. Healthcare Mater. 2015, 4, 377–384.

• 2014

  Yuzhou Wu*, Dongsheng Liu*, Tanja Weil*. Programmable protein–DNA hybrid hydrogels for the immobilization and release of functional proteins. Chem. Commun., 2014,50, 14620-14622.

  David Yuen Wah Ng#, Yuzhou Wu#, Seah Ling Kuan and Tanja Weil*. Programming Supramolecular Biohybrids as Precision Therapeutics. Acc. Chem. Res., 2014, 47, 3471-3480. (#Shared first authorship).

  Chuang Li, Ping Chen, Yu Shao, Xu Zhou, Yuzhou Wu, Zhongqiang Yang, Zhibo Li, Tanja Weil, Dongsheng Liu*, A writable polypeptide-DNA hydrogel with rationally designed multi-modification sites, Small, 2014, 11, 1138-1143.

  Tao Wang, David Y. W. Ng, Yuzhou Wu, Jessica Thomas, Thuy TamTran and Tanja Weil*. Bis-sulfide bioconjugates for glutathione triggered tumor responsive drug release. Chem. Commun., 2014, 50, 1116-1118.

  David Y. W. Ng, Matthias Arzt, Yuzhou Wu, Seah Ling Kuan, Markus Lamla, Tanja Weil*. Constructing Hybrid Protein Zymogens through Protective Dendritic Assembly. Angew. Chem. Int. Ed. 2014, 53, 324-328.

  Christoph Meier, Yuzhou Wu, Goutam Pramanik, Tanja Weil*. Self-Assembly of High Molecular Weight Polypeptide Copolymers Studied via Diffusion Limited Aggregation. Biomacromolecules, 2014, 15, 219-227.

  David Yuen Wah Ng, Holger Barth*, Tanja Weil*. Efficient Delivery of p53 and Cytochrome C by Supramolecular Assembly of a Dendritic Multi-Domain Delivery System. Adv. Healthcare Mater., 2014, 2, 1620-1629.

• 2013

  Yuzhou Wu, Tanja Weil*. A Core-shell Albumin Copolymer Nanotransporter for High Capacity Loading and Two-step Release of Doxorubicin with Enhanced Anti‐Leukemia Activity. Adv. Healthcare Mater. 2013, 2, 884–894.

  Diego Pesce#, Yuzhou Wu#, Anke Kolbe, Tanja Weil* and Andreas Herrmann*. Enhancing Cellular Uptake of GFP via Unfolded Supercharged Protein Tags. Biomaterials, 2013, 34, 4360. (#Shared first authorship)

  Seah Ling Kuan, Yuzhou Wu, Tanja Weil*.pH Responsive Janus-like Supramolecular Fusion Proteins for Functional Protein Delivery. J. Am. Chem. Soc. 2013, 135 (46), 17254–17257.

  Jana Hedrich, Yuzhou Wu, Manfred Schmidt. Polymer Complexes in Biological Applications.Adv. Polym. Sci. 2013, doi: 10.1007/12_2013_229. (Book Chapter).

  Tao Wang, Yuzhou Wu, Tanja Weil*. A Versatile and Orthogonal Approach for the Cross-Conjugation of DNA, Proteins and Peptides via the pH Switch. Chem. Sci., 2013, 4, 1889-1894.

  Seah Ling Kuan, Yuzhou Wu, Tanja Weil*. Precision Biopolymers from Protein Precursors for Biomedical Applications. Macromol Rapid Commun., 2013, 34, 380.

  Seah Ling Kuan, Yuzhou Wu, Tanja Weil*. Dendronized Albumin Biohybrids as Efficient Core-Shell Doxorubicin Delivery Systems” Biomacromolecules, 2013, 14 (2): 367–376.

• 2012

  Yuzhou Wu, Goutam Pramanik, Klaus Eisele, Tanja Weil*. Convenient Approach to Polypeptide Copolymers Derived from Native Proteins. Biomacromolecules, 2012, 13(6):1890-1898.

  Yuzhou Wu, Tao Wang, David Y.W. Ng, Tanja Weil*. Multifunctional Polypeptide-PEO Nanoreactors via the Hydrophobic Switch. Macromol. Rapid Commun., 2012, 33(17):1474-1481.

  Yuzhou Wu, Tanja Weil*. An Efficient Approach for Preparing Giant Polypeptide Triblock Copolymers by Protein Dimerization. Macromol. Rapid Commun., 2012, 33(15):1304-1309.

  Yuzhou Wu, Kai Shih Er, Arvind Ramanathan, Subhash Vasudevan, Tanja Weil*. Nano-sized Albumin-copolymer Micelles for Efficient Doxorubicin Delivery. Biointerphases. 2012, 7(1-4):5.

  Yasar Akdogan, Yuzhou Wu, Klaus Eisele, Manuela Schaz, Tanja Weil* and Dariush Hinderberger*. Host-Guest Interactions in Polycationic Human Serum Albumin Bioconjugates. Soft Matter, 2012, 8(43): 11106-11114.

  Yuzhou Wu, Tanja Weil*. A Quantum Dot Photoswitch for DNA Detection, Gene Transfection, and Live-Cell Imaging. Small, 2012, 8(22): 3465–3475. (Cover article)

• 2011

  Tanja Weil, Goutam Pramanik, Yuzhou Wu. Protein-based copolymers for bioimaging and drug delivery applications. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 2011, 52(1): no page given.

• 2010

  Yuzhou Wu, Yinthai Chan* and Tanja Weil*. “pH-Responsive Quantum Dots via an Albumin Polymer Surface Coating” J. Am. Chem. Soc., 2010, 51(1): 786-787.

  Yuzhou Wu, Tanja Weil. Multifunctional protein- hybrid and its applications in quantum dot coatings. Polymer Preprints (American Chemical Society, Division of Polymer Chemistry), 2010, 51(1): 786-787.